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Mitochondria-Derived Reactive Intermediate Species Mediate Asbestos-Induced Genotoxicity and Oxidative Stress–Responsive Signaling Pathways

Background: The incidence of asbestos-induced human cancers is increasing worldwide, and considerable evidence suggests that reactive oxygen species (ROS) are important mediators of these diseases. Our previous studies suggested that mitochondria might be involved in the initiation of oxidative stre...

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Detalles Bibliográficos
Autores principales: Huang, Sarah X.L., Partridge, Michael A., Ghandhi, Shanaz A., Davidson, Mercy M., Amundson, Sally A., Hei, Tom K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385428/
https://www.ncbi.nlm.nih.gov/pubmed/22398240
http://dx.doi.org/10.1289/ehp.1104287

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