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Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?

Ebola hemorrhagic fever (EHF) and Marburg hemorrhagic fever (MHF) are rare viral diseases, endemic to central Africa. The overall burden of EHF and MHF is small in comparison to the more common protozoan, helminth, and bacterial diseases typically referred to as neglected tropical diseases (NTDs). H...

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Detalles Bibliográficos
Autores principales: MacNeil, Adam, Rollin, Pierre E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385614/
https://www.ncbi.nlm.nih.gov/pubmed/22761967
http://dx.doi.org/10.1371/journal.pntd.0001546
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author MacNeil, Adam
Rollin, Pierre E.
author_facet MacNeil, Adam
Rollin, Pierre E.
author_sort MacNeil, Adam
collection PubMed
description Ebola hemorrhagic fever (EHF) and Marburg hemorrhagic fever (MHF) are rare viral diseases, endemic to central Africa. The overall burden of EHF and MHF is small in comparison to the more common protozoan, helminth, and bacterial diseases typically referred to as neglected tropical diseases (NTDs). However, EHF and MHF outbreaks typically occur in resource-limited settings, and many aspects of these outbreaks are a direct consequence of impoverished conditions. We will discuss aspects of EHF and MHF disease, in comparison to the “classic” NTDs, and examine potential ways forward in the prevention and control of EHF and MHF in sub-Saharan Africa, as well as examine the potential for application of novel vaccines or antiviral drugs for prevention or control of EHF and MHF among populations at highest risk for disease.
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spelling pubmed-33856142012-07-03 Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases? MacNeil, Adam Rollin, Pierre E. PLoS Negl Trop Dis Review Ebola hemorrhagic fever (EHF) and Marburg hemorrhagic fever (MHF) are rare viral diseases, endemic to central Africa. The overall burden of EHF and MHF is small in comparison to the more common protozoan, helminth, and bacterial diseases typically referred to as neglected tropical diseases (NTDs). However, EHF and MHF outbreaks typically occur in resource-limited settings, and many aspects of these outbreaks are a direct consequence of impoverished conditions. We will discuss aspects of EHF and MHF disease, in comparison to the “classic” NTDs, and examine potential ways forward in the prevention and control of EHF and MHF in sub-Saharan Africa, as well as examine the potential for application of novel vaccines or antiviral drugs for prevention or control of EHF and MHF among populations at highest risk for disease. Public Library of Science 2012-06-26 /pmc/articles/PMC3385614/ /pubmed/22761967 http://dx.doi.org/10.1371/journal.pntd.0001546 Text en This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. https://creativecommons.org/publicdomain/zero/1.0/ This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
spellingShingle Review
MacNeil, Adam
Rollin, Pierre E.
Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?
title Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?
title_full Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?
title_fullStr Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?
title_full_unstemmed Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?
title_short Ebola and Marburg Hemorrhagic Fevers: Neglected Tropical Diseases?
title_sort ebola and marburg hemorrhagic fevers: neglected tropical diseases?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385614/
https://www.ncbi.nlm.nih.gov/pubmed/22761967
http://dx.doi.org/10.1371/journal.pntd.0001546
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