Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases

Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role. The effects induced by prostaglandins might be mediated by activation of their known receptors...

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Detalles Bibliográficos
Autores principales: Lima, Isabel Vieira de Assis, Bastos, Leandro Francisco Silva, Limborço-Filho, Marcelo, Fiebich, Bernd L., de Oliveira, Antonio Carlos Pinheiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385693/
https://www.ncbi.nlm.nih.gov/pubmed/22778499
http://dx.doi.org/10.1155/2012/946813
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author Lima, Isabel Vieira de Assis
Bastos, Leandro Francisco Silva
Limborço-Filho, Marcelo
Fiebich, Bernd L.
de Oliveira, Antonio Carlos Pinheiro
author_facet Lima, Isabel Vieira de Assis
Bastos, Leandro Francisco Silva
Limborço-Filho, Marcelo
Fiebich, Bernd L.
de Oliveira, Antonio Carlos Pinheiro
author_sort Lima, Isabel Vieira de Assis
collection PubMed
description Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role. The effects induced by prostaglandins might be mediated by activation of their known receptors or by nonclassical mechanisms. In the present paper, we discuss the evidences that link prostaglandins, as well as the enzymes that produce them, to some neurological diseases.
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spelling pubmed-33856932012-07-09 Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases Lima, Isabel Vieira de Assis Bastos, Leandro Francisco Silva Limborço-Filho, Marcelo Fiebich, Bernd L. de Oliveira, Antonio Carlos Pinheiro Mediators Inflamm Review Article Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role. The effects induced by prostaglandins might be mediated by activation of their known receptors or by nonclassical mechanisms. In the present paper, we discuss the evidences that link prostaglandins, as well as the enzymes that produce them, to some neurological diseases. Hindawi Publishing Corporation 2012 2012-06-18 /pmc/articles/PMC3385693/ /pubmed/22778499 http://dx.doi.org/10.1155/2012/946813 Text en Copyright © 2012 Isabel Vieira de Assis Lima et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Lima, Isabel Vieira de Assis
Bastos, Leandro Francisco Silva
Limborço-Filho, Marcelo
Fiebich, Bernd L.
de Oliveira, Antonio Carlos Pinheiro
Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases
title Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases
title_full Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases
title_fullStr Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases
title_full_unstemmed Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases
title_short Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases
title_sort role of prostaglandins in neuroinflammatory and neurodegenerative diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385693/
https://www.ncbi.nlm.nih.gov/pubmed/22778499
http://dx.doi.org/10.1155/2012/946813
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