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New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levels

Over calendar time, HIV-1 evolves considerably faster within individuals than it does at the epidemic level. This is a surprising observation since, from basic population genetic theory, we would expect the genetic substitution rate to be similar across different levels of biological organization. T...

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Detalles Bibliográficos
Autores principales: Lythgoe, Katrina A., Fraser, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385732/
https://www.ncbi.nlm.nih.gov/pubmed/22593106
http://dx.doi.org/10.1098/rspb.2012.0595

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