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New insights into the evolutionary rate of HIV-1 at the within-host and epidemiological levels
Over calendar time, HIV-1 evolves considerably faster within individuals than it does at the epidemic level. This is a surprising observation since, from basic population genetic theory, we would expect the genetic substitution rate to be similar across different levels of biological organization. T...
Autores principales: | Lythgoe, Katrina A., Fraser, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385732/ https://www.ncbi.nlm.nih.gov/pubmed/22593106 http://dx.doi.org/10.1098/rspb.2012.0595 |
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