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Vasoconstriction Potency Induced by Aminoamide Local Anesthetics Correlates with Lipid Solubility
Aminoamide local anesthetics induce vasoconstriction in vivo and in vitro. The goals of this in vitro study were to investigate the potency of local anesthetic-induced vasoconstriction and to identify the physicochemical property (octanol/buffer partition coefficient, pKa, molecular weight, or poten...
Autores principales: | Sung, Hui-Jin, Ok, Seong-Ho, Sohn, Jin-Young, Son, Yong Hyeok, Kim, Jun Kyu, Lee, Soo Hee, Han, Jeong Yeol, Lim, Dong Hoon, Shin, Il-Woo, Lee, Heon-Keun, Chung, Young-Kyun, Choi, Mun-Jeoung, Sohn, Ju-Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3385964/ https://www.ncbi.nlm.nih.gov/pubmed/22778542 http://dx.doi.org/10.1155/2012/170958 |
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