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A Broad Requirement for TLS Polymerases η and κ, and Interacting Sumoylation and Nuclear Pore Proteins, in Lesion Bypass during C. elegans Embryogenesis

Translesion synthesis (TLS) polymerases are specialized DNA polymerases capable of inserting nucleotides opposite DNA lesions that escape removal by dedicated DNA repair pathways. TLS polymerases allow cells to complete DNA replication in the presence of damage, thereby preventing checkpoint activat...

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Detalles Bibliográficos
Autores principales:	Roerink, Sophie F., Koole, Wouter, Stapel, L. Carine, Romeijn, Ron J., Tijsterman, Marcel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386174/ https://www.ncbi.nlm.nih.gov/pubmed/22761594 http://dx.doi.org/10.1371/journal.pgen.1002800

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