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CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson Disease, Alzheimer Disease and Huntington Disease. PUMA (p53 upregulated modulator of apoptosis) and BIM (BCL2 interacting mediator of cell death), pro-apoptotic BH3 doma...

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Detalles Bibliográficos
Autores principales: Ghosh, Arindam P., Klocke, Barbara J., Ballestas, Mary E., Roth, Kevin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386252/
https://www.ncbi.nlm.nih.gov/pubmed/22761832
http://dx.doi.org/10.1371/journal.pone.0039586