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Enzymatic Degradation of PrP(Sc) by a Protease Secreted from Aeropyrum pernix K1

BACKGROUND: An R30 fraction from the growth medium of Aeropyrum pernix was analyzed for the protease that can digest the pathological prion protein isoform (PrP(Sc)) from different species (human, bovine, deer and mouse). METHODOLOGY/PRINCIPAL FINDINGS: Degradation of the PrP(Sc) isoform by the R30...

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Detalles Bibliográficos
Autores principales:	Šnajder, Marko, Vilfan, Tanja, Černilec, Maja, Rupreht, Ruth, Popović, Mara, Juntes, Polona, Šerbec, Vladka Čurin, Ulrih, Nataša Poklar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386259/ https://www.ncbi.nlm.nih.gov/pubmed/22761822 http://dx.doi.org/10.1371/journal.pone.0039548

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