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Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors

Tau hyperphosphorylation is one hallmark of Alzheimer's disease (AD) pathology. Pharmaceutical companies have thus developed kinase inhibitors aiming to reduce tau hyperphosphorylation. One obstacle in screening for tau kinase inhibitors is the low phosphorylation levels of AD-related phospho-e...

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Detalles Bibliográficos
Autores principales:	Bretteville, Alexis, Marcouiller, François, Julien, Carl, El Khoury, Noura B., Petry, Franck R., Poitras, Isabelle, Mouginot, Didier, Lévesque, Georges, Hébert, Sébastien S., Planel, Emmanuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386519/ https://www.ncbi.nlm.nih.gov/pubmed/22761989 http://dx.doi.org/10.1038/srep00480

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