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Cytotoxicity and Glycan-Binding Properties of an 18 kDa Lectin Isolated from the Marine Sponge Halichondria okadai
A divalent cation-independent lectin—HOL-18, with cytotoxic activity against leukemia cells, was purified from a demosponge, Halichondria okadai. HOL-18 is a 72 kDa tetrameric lectin that consists of four non-covalently bonded 18 kDa subunits. Hemagglutination activity of the lectin was strongly inh...
Autores principales: | Matsumoto, Ryo, Fujii, Yuki, Kawsar, Sarkar M. A., Kanaly, Robert A., Yasumitsu, Hidetaro, Koide, Yasuhiro, Hasan, Imtiaj, Iwahara, Chihiro, Ogawa, Yukiko, Im, Chang Hun, Sugawara, Shigeki, Hosono, Masahiro, Nitta, Kazuo, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386633/ https://www.ncbi.nlm.nih.gov/pubmed/22778903 http://dx.doi.org/10.3390/toxins4050323 |
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