Cargando…

CD98 Increases Renal Epithelial Cell Proliferation by Activating MAPKs

CD98 heavy chain (CD98hc) is a multifunctional transmembrane spanning scaffolding protein whose extracellular domain binds with light chain amino acid transporters (Lats) to form the heterodimeric amino acid transporters (HATs). It also interacts with β1 and β3 integrins by its transmembrane and cyt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bulus, Nada, Feral, Chloe, Pozzi, Ambra, Zent, Roy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386947/ https://www.ncbi.nlm.nih.gov/pubmed/22768207 http://dx.doi.org/10.1371/journal.pone.0040026

Ejemplares similares

CD98hc facilitates B cell proliferation and adaptive humoral immunity
por: Cantor, Joseph, et al.
Publicado: (2009)

Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice
por: Bulus, Nada, et al.
Publicado: (2021)

CD98hc (SLC3A2) regulation of skin homeostasis wanes with age
por: Boulter, Etienne, et al.
Publicado: (2013)

Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2)
por: Fogelstrand, Per, et al.
Publicado: (2009)

Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells
por: Miller, Charles G., et al.
Publicado: (2014)

CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling
por: Féral, Chloé C., et al.
Publicado: (2007)

miR-98 inhibits cell proliferation and induces cell apoptosis by targeting MAPK6 in HUVECs
por: Hu, Chuanxian, et al.
Publicado: (2018)

Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation
por: Taguchi, Kensei, et al.
Publicado: (2022)

Antitumor activity of an anti‐CD98 antibody
por: Hayes, Gregory M., et al.
Publicado: (2015)

Salt-bridge modulates differential calcium-mediated ligand binding to integrin α1- and α2-I domains
por: Brown, Kyle L., et al.
Publicado: (2018)

Investigation of the Gamow-Teller decay of $^{98}$Cd
por: Barden, R, et al.
Publicado: (1987)

Investigation of the Gamow-Teller decay of $^{98}$Cd
por: Barden, R, et al.
Publicado: (1987)

Integrin α1/Akita double knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy
por: Yu, Ling, et al.
Publicado: (2012)

CD98 Heavy Chain Is a Potent Positive Regulator of CD4(+) T Cell Proliferation and Interferon-γ Production In Vivo
por: Kurihara, Takeshi, et al.
Publicado: (2015)

Arrestins regulate cell spreading and motility via focal adhesion dynamics
por: Cleghorn, Whitney M., et al.
Publicado: (2015)

Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway
por: Lan, Ting, et al.
Publicado: (2023)

MAPKs and Signal Transduction in the Control of Gastrointestinal Epithelial Cell Proliferation and Differentiation
por: Osaki, Luciana H., et al.
Publicado: (2013)

Human Endometrial CD98 Is Essential for Blastocyst Adhesion
por: Domínguez, Francisco, et al.
Publicado: (2010)

CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior
por: Poettler, Marina, et al.
Publicado: (2013)

Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury
por: Xie, Qionghong, et al.
Publicado: (2022)

p47phox contributes to albuminuria and kidney fibrosis in mice
por: Wang, Hongtao, et al.
Publicado: (2015)

Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function
por: Lu, Zhenwei, et al.
Publicado: (2016)

Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance
por: Williams, Ashley S., et al.
Publicado: (2017)

Structure basis for AA98 inhibition on the activation of endothelial cells mediated by CD146
por: Chen, Xuehui, et al.
Publicado: (2021)

Ecto-Phosphorylation of CD98 Regulates Cell-Cell Interactions
por: Nguyen, Hang Thi Thu, et al.
Publicado: (2008)

Conditional deletion of CD98hc inhibits osteoclast development
por: Tsumura, Hideki, et al.
Publicado: (2015)

CD98hc is a target for brain delivery of biotherapeutics
por: Chew, Kylie S., et al.
Publicado: (2023)

Membrane-Type 4 Matrix Metalloproteinase (MT4-MMP) Modulates Water Homeostasis in Mice
por: Srichai, Manakan B., et al.
Publicado: (2011)

Identification of anti-CD98 antibody mimotopes for inducing antibodies with antitumor activity by mimotope immunization
por: Saito, Misa, et al.
Publicado: (2014)

98 : derrota pírrica /
Publicado: (2000)

CD98 Positive Eosinophils Contribute to T Helper 1 Pattern Inflammation
por: Xue, Fu-Min, et al.
Publicado: (2012)

Extracellular domain of CD98hc is required for early murine development
por: Sato, Yukiyasu, et al.
Publicado: (2011)

Observation of a core-excited E4 isomer in ${98}Cd$
por: Blazhev, A, et al.
Publicado: (2004)

ORBIS '98
Publicado: (1998)

WA98
por: Königsmann, K C
Publicado: (1995)

miR-98-5p Alleviated Epithelial-to-Mesenchymal Transition and Renal Fibrosis via Targeting Hmga2 in Diabetic Nephropathy
por: Zhu, Yingchun, et al.
Publicado: (2019)

TRIB3 Promotes the Proliferation and Invasion of Renal Cell Carcinoma Cells via Activating MAPK Signaling Pathway
por: Hong, Baoan, et al.
Publicado: (2019)

Inhibition of IL-8-mediated endothelial adhesion, VSMCs proliferation and migration by siRNA-TMEM98 suggests TMEM98's emerging role in atherosclerosis
por: Lv, Guangxin, et al.
Publicado: (2017)

Internalization of Garlic-Derived Nanovesicles on Liver Cells is Triggered by Interaction With CD98
por: Song, Heliang, et al.
Publicado: (2020)

CD98 heavy chain as a prognostic biomarker and target for cancer treatment
por: Xia, Pu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0c4nn5dbrijl4u2eaj4iu6lp0t