CD28 Costimulation Regulates Genome-Wide Effects on Alternative Splicing

CD28 is the major costimulatory receptor required for activation of naïve T cells, yet CD28 costimulation affects the expression level of surprisingly few genes over those altered by TCR stimulation alone. Alternate splicing of genes adds diversity to the proteome and contributes to tissue-specific...

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Detalles Bibliográficos
Autores principales: Butte, Manish J., Lee, Sun Jung, Jesneck, Jonathan, Keir, Mary E., Haining, W. Nicholas, Sharpe, Arlene H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386953/
https://www.ncbi.nlm.nih.gov/pubmed/22768209
http://dx.doi.org/10.1371/journal.pone.0040032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386953/
https://www.ncbi.nlm.nih.gov/pubmed/22768209
http://dx.doi.org/10.1371/journal.pone.0040032

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