Extracellular Ig(C2) Constant Domains of CEACAMs Mediate PI3K Sensitivity during Uptake of Pathogens

BACKGROUND: Several pathogenic bacteria utilize receptors of the CEACAM family to attach to human cells. Binding to different members of this receptor family can result in uptake of the bacteria. Uptake of Neisseria gonorrhoeae, a Gram-negative human pathogen, via CEACAMs found on epithelial cells,...

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Detalles Bibliográficos
Autores principales: Voges, Maike, Bachmann, Verena, Naujoks, Jan, Kopp, Kathrin, Hauck, Christof R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386982/
https://www.ncbi.nlm.nih.gov/pubmed/22768164
http://dx.doi.org/10.1371/journal.pone.0039908

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