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Controlled Breast Cancer Microarrays for the Deconvolution of Cellular Multilayering and Density Effects upon Drug Responses

BACKGROUND: Increasing evidence shows that the cancer microenvironment affects both tumorigenesis and the response of cancer to drug treatment. Therefore in vitro models that selectively reflect characteristics of the in vivo environment are greatly needed. Current methods allow us to screen the eff...

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Detalles Bibliográficos
Autores principales: Håkanson, Maria, Kobel, Stefan, Lutolf, Matthias P., Textor, Marcus, Cukierman, Edna, Charnley, Mirren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387021/
https://www.ncbi.nlm.nih.gov/pubmed/22792141
http://dx.doi.org/10.1371/journal.pone.0040141