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Activated Human CD4+CD45RO+ Memory T-Cells Indirectly Inhibit NLRP3 Inflammasome Activation through Downregulation of P2X7R Signalling

Inflammasomes are multi-protein complexes that control the production of pro-inflammatory cytokines such as IL-1β. Inflammasomes play an important role in the control of immunity to tumors and infections, and also in autoimmune diseases, but the mechanisms controlling the activation of human inflamm...

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Detalles Bibliográficos
Autores principales:	Beynon, Vanessa, Quintana, Francisco J., Weiner, Howard L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387029/ https://www.ncbi.nlm.nih.gov/pubmed/22768094 http://dx.doi.org/10.1371/journal.pone.0039576

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