Inhibition of Casein Kinase 2 Modulates XBP1-GRP78 Arm of Unfolded Protein Responses in Cultured Glial Cells

Stress signals cause abnormal proteins to accumulate in the endoplasmic reticulum (ER). Such stress is known as ER stress, which has been suggested to be involved in neurodegenerative diseases, diabetes, obesity and cancer. ER stress activates the unfolded protein response (UPR) to reduce levels of...

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Detalles Bibliográficos
Autores principales: Hosoi, Toru, Korematsu, Kenta, Horie, Naohiro, Suezawa, Takahiro, Okuma, Yasunobu, Nomura, Yasuyuki, Ozawa, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387139/
https://www.ncbi.nlm.nih.gov/pubmed/22768244
http://dx.doi.org/10.1371/journal.pone.0040144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387139/
https://www.ncbi.nlm.nih.gov/pubmed/22768244
http://dx.doi.org/10.1371/journal.pone.0040144

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