Cargando…
Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences
Single-stranded DNA (ssDNA) is characterized by high conformational flexibility that allows these molecules to adopt a variety of conformations. Here we used native polyacrylamide gel electrophoresis (PAGE), circular dichroism (CD) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy to sh...
Autores principales: | Taqi, Malik Mumtaz, Wärmländer, Sebastian K. T. S., Yamskova, Olga, Madani, Fatemeh, Bazov, Igor, Luo, Jinghui, Zubarev, Roman, Verbeek, Dineke, Gräslund, Astrid, Bakalkin, Georgy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387154/ https://www.ncbi.nlm.nih.gov/pubmed/22768096 http://dx.doi.org/10.1371/journal.pone.0039605 |
Ejemplares similares
-
Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics
por: Bazov, Igor, et al.
Publicado: (2018) -
Upregulated dynorphin opioid peptides mediate alcohol-induced learning and memory impairment
por: Kuzmin, A, et al.
Publicado: (2013) -
Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system
por: Sirohi, Sunil, et al.
Publicado: (2012) -
Enhanced gene repair mediated by methyl-CpG-modified single-stranded oligonucleotides
por: Bertoni, Carmen, et al.
Publicado: (2009) -
CpG Oligonucleotides as Cancer Vaccine Adjuvants
por: Shirota, Hidekazu, et al.
Publicado: (2015)