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Intrathecal Injection of Spironolactone Attenuates Radicular Pain by Inhibition of Spinal Microglia Activation in a Rat Model

BACKGROUND: Microglia might play an important role in nociceptive processing and hyperalgesia by neuroinflammatory process. Mineralocorticoid receptor (MR) expressed on microglia might play a central role in the modulation of microglia activity. However the roles of microglia and MR in radicular pai...

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Detalles Bibliográficos
Autores principales:	Sun, Yu-e, Peng, Liangyu, Sun, Xiaofeng, Bo, Jinhua, Yang, Dong, Zheng, Yaguo, Liu, Chenglong, Zhu, Beibei, Ma, Zhengliang, Gu, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387194/ https://www.ncbi.nlm.nih.gov/pubmed/22768159 http://dx.doi.org/10.1371/journal.pone.0039897

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