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Deficiency of Thioredoxin Binding Protein-2 (TBP-2) Enhances TGF-β Signaling and Promotes Epithelial to Mesenchymal Transition

BACKGROUND: Transforming growth factor beta (TGF-β) has critical roles in regulating cell growth, differentiation, apoptosis, invasion and epithelial-mesenchymal transition (EMT) of various cancer cells. TGF-β-induced EMT is an important step during carcinoma progression to invasion state. Thioredox...

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Detalles Bibliográficos
Autores principales:	Masaki, So, Masutani, Hiroshi, Yoshihara, Eiji, Yodoi, Junji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387201/ https://www.ncbi.nlm.nih.gov/pubmed/22768160 http://dx.doi.org/10.1371/journal.pone.0039900

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