Phenotype Selection Reveals Coevolution of Muscle Glycogen and Protein and PTEN as a Gate Keeper for the Accretion of Muscle Mass in Adult Female Mice

We have investigated molecular mechanisms for muscle mass accretion in a non-inbred mouse model (DU6P mice) characterized by extreme muscle mass. This extreme muscle mass was developed during 138 generations of phenotype selection for high protein content. Due to the repeated trait selection a compl...

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Detalles Bibliográficos
Autores principales: Sawitzky, Mandy, Zeissler, Anja, Langhammer, Martina, Bielohuby, Maximilian, Stock, Peggy, Hammon, Harald M., Görs, Solvig, Metges, Cornelia C., Stoehr, Barbara J. M., Bidlingmaier, Martin, Fromm-Dornieden, Carolin, Baumgartner, Bernhard G., Christ, Bruno, Brenig, Bertram, Binder, Gerhard, Metzger, Friedrich, Renne, Ulla, Hoeflich, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387210/
https://www.ncbi.nlm.nih.gov/pubmed/22768110
http://dx.doi.org/10.1371/journal.pone.0039711

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