Cargando…
Cell Invasion by Neisseria meningitidis Requires a Functional Interplay between the Focal Adhesion Kinase, Src and Cortactin
Entry of Neisseria meningitidis (the meningococcus) into human brain microvascular endothelial cells (HBMEC) is mediated by fibronectin or vitronectin bound to the surface protein Opc forming a bridge to the respective integrins. This interaction leads to cytoskeletal rearrangement and uptake of men...
Autores principales: | Slanina, Heiko, Hebling, Sabrina, Hauck, Christoph R., Schubert-Unkmeir, Alexandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387252/ https://www.ncbi.nlm.nih.gov/pubmed/22768099 http://dx.doi.org/10.1371/journal.pone.0039613 |
Ejemplares similares
-
Neisseria meningitidis Induces Brain Microvascular Endothelial Cell Detachment from the Matrix and Cleavage of Occludin: A Role for MMP-8
por: Schubert-Unkmeir, Alexandra, et al.
Publicado: (2010) -
Differential Activation of Acid Sphingomyelinase and Ceramide Release Determines Invasiveness of Neisseria meningitidis into Brain Endothelial Cells
por: Simonis, Alexander, et al.
Publicado: (2014) -
Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility
por: Wang, Wenqi, et al.
Publicado: (2011) -
Super-Resolution Microscopy Reveals Local Accumulation of Plasma Membrane Gangliosides at Neisseria meningitidis Invasion Sites
por: Schlegel, Jan, et al.
Publicado: (2019) -
A Comprehensive Review on the Interplay between Neisseria spp. and Host Sphingolipid Metabolites
por: Peters, Simon, et al.
Publicado: (2021)