Cargando…

B Cell Repopulation After Alemtuzumab Induction—Transient Increase in Transitional B Cells and Long-Term Dominance of Naïve B Cells

In organ transplantation, the composition of the B-cell compartment is increasingly identified as an important determinant for graft outcome. Whereas naïve and transitional B cells have been associated with long-term allograft survival and operational tolerance, memory B cells have been linked to de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heidt, S, Hester, J, Shankar, S, Friend, P J, Wood, K J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Inc 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387484/ https://www.ncbi.nlm.nih.gov/pubmed/22420490 http://dx.doi.org/10.1111/j.1600-6143.2012.04012.x

Ejemplares similares

Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis
por: Gilmore, Wendy, et al.
Publicado: (2020)

Alemtuzumab as Antirejection Therapy: T Cell Repopulation and Cytokine Responsiveness
por: Bouvy, Anne P., et al.
Publicado: (2016)

B cells: deplete, repopulate, vaccinate
por: Phillips, Robert
Publicado: (2022)

Alemtuzumab induction therapy in solid organ transplantation
por: Friend, Peter J
Publicado: (2013)

CD19 B cell repopulation after ocrelizumab, alemtuzumab and cladribine: Implications for SARS-CoV-2 vaccinations in multiple sclerosis
por: Baker, David, et al.
Publicado: (2022)

Monitoring B-cell repopulation after depletion therapy in neurologic patients
por: Ellwardt, Erik, et al.
Publicado: (2018)

Rescue therapy with alemtuzumab in B cell/antibody-mediated multiple sclerosis
por: Akgün, Katja, et al.
Publicado: (2018)

Influence of anaesthetics on tumour-cell kill and repopulation in B16 melanoma treated with melphalan.
por: Peacock, J. H., et al.
Publicado: (1978)

Human transitional and IgM(low) mature naïve B cells preserve permissive B‐cell receptors
por: Zhang, Zhiguo, et al.
Publicado: (2021)

Alemtuzumab in the treatment of fludarabine refractory B-cell chronic lymphocytic leukemia (CLL)
por: Montillo, Marco, et al.
Publicado: (2008)

Evidence of B-cell dysregulation in severe CNS inflammation after alemtuzumab therapy
por: Rinaldi, Francesca, et al.
Publicado: (2017)

Vitiligo after alemtuzumab treatment: Secondary autoimmunity is not all about B cells
por: Ruck, Tobias, et al.
Publicado: (2018)

Both cladribine and alemtuzumab may effect MS via B-cell depletion
por: Baker, David, et al.
Publicado: (2017)

Role of B Cell Profile for Predicting Secondary Autoimmunity in Patients Treated With Alemtuzumab
por: Walo-Delgado, Paulette Esperanza, et al.
Publicado: (2021)

Transiently antigen-primed B cells return to naive-like state in absence of T-cell help
por: Turner, Jackson S., et al.
Publicado: (2017)

Apoptosis induction and tumor cell repopulation: The yin and yang of radiotherapy
por: Lauber, Kirsten, et al.
Publicado: (2011)

Efficacy of Rituximab Outlasts B-Cell Repopulation in Multiple Sclerosis: Time to Rethink Dosing?
por: Claverie, Roxane, et al.
Publicado: (2023)

Silencing of B Cell Receptor Signals in Human Naive B Cells
por: Feldhahn, Niklas, et al.
Publicado: (2002)

Restoration of regulatory B cell deficiency following alemtuzumab therapy in patients with relapsing multiple sclerosis
por: Kim, Yeseul, et al.
Publicado: (2018)

Alemtuzumab induction in pediatric kidney transplantation
por: Kaabak, Michael M, et al.
Publicado: (2013)

Extended interval dosing of ocrelizumab modifies the repopulation of B cells without altering the clinical efficacy in multiple sclerosis
por: Rodriguez-Mogeda, Carla, et al.
Publicado: (2023)

Repopulating glioma cell lines
por: Tuma, Rabiya
Publicado: (2004)

Delayed B cell repopulation after rituximab treatment in multiple sclerosis patients with expanded adaptive natural killer cells
por: Moreira, Antía, et al.
Publicado: (2022)

Mitigating alemtuzumab-associated autoimmunity in MS: A “whack-a-mole” B-cell depletion strategy
por: Meltzer, Ethan, et al.
Publicado: (2020)

B Cell Immunity in Solid Organ Transplantation
por: Karahan, Gonca E., et al.
Publicado: (2017)

Aberrant B Cell Receptor Signaling in Naïve B Cells from Patients with Idiopathic Pulmonary Fibrosis
por: Neys, Stefan F. H., et al.
Publicado: (2021)

T cell-dependent induction of NF-kappa B in B cells
Publicado: (1993)

Alemtuzumab Induction and Delayed Acute Rejection in Steroid-Free Simultaneous Pancreas-Kidney Transplant Recipients
por: Bank, Jonna R., et al.
Publicado: (2016)

Immune reconstitution following alemtuzumab therapy is characterized by exhausted T cells, increased regulatory control of proinflammatory T cells and reduced B cell control
por: von Essen, Marina Rode, et al.
Publicado: (2023)

Endogenous antigen tunes the responsiveness of naive B cells but not T cells
por: Zikherman, Julie, et al.
Publicado: (2012)

Evidence for enhanced Bruton’s tyrosine kinase activity in transitional and naïve B cells of patients with granulomatosis with polyangiitis
por: von Borstel, Anouk, et al.
Publicado: (2019)

Differential Cytokine Utilization and Tissue Tropism Results in Distinct Repopulation Kinetics of Naïve vs. Memory T Cells in Mice
por: Kim, Hye Kyung, et al.
Publicado: (2019)

Thymic hyperplasia after chemotherapy in adults with mature B cell lymphoma and its influence on thymic output and CD4(+) T cells repopulation
por: Sun, Dao-Ping, et al.
Publicado: (2016)

CD19 Cell Count at Baseline Predicts B Cell Repopulation at 6 and 12 Months in Multiple Sclerosis Patients Treated with Ocrelizumab
por: Abbadessa, Gianmarco, et al.
Publicado: (2021)

Early B cells repopulation in multiple sclerosis patients treated with rituximab is not predictive of a risk of relapse or clinical progression
por: Dorcet, Guillaume, et al.
Publicado: (2022)

Widespread B cell perturbations in HIV-1 infection afflict naive and marginal zone B cells
por: Liechti, Thomas, et al.
Publicado: (2019)

Quick and easy purification of murine untouched naive B cells or germinal center B cells by MACS
por: Ramezani-Rad, Parham, et al.
Publicado: (2021)

NF-κB Regulates Mesenchymal Transition for the Induction of Non-Small Cell Lung Cancer Initiating Cells
por: Kumar, Manish, et al.
Publicado: (2013)

Alemtuzumab
por: Tridente, Giuseppe
Publicado: (2013)

Transitional B cells are the target of negative selection in the B cell compartment
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_8b2hm5oop2aegfinud7k9q3tnl