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Mild-stretch mechanical ventilation upregulates toll-like receptor 2 and sensitizes the lung to bacterial lipopeptide
INTRODUCTION: Mechanical ventilation (MV) could prime the lung toward an inflammatory response if exposed to another insult such as bacterial invasion. The underlying mechanisms are not so far clear. Toll-like receptors (TLRs) allow the host to recognize selectively bacterial pathogens and in turn t...
Autores principales: | Charles, Pierre-Emmanuel, Tissières, Pierre, Barbar, Saber Davide, Croisier, Delphine, Dufour, Julien, Dunn-Siegrist, Irène, Chavanet, Pascal, Pugin, Jérôme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387624/ https://www.ncbi.nlm.nih.gov/pubmed/21794115 http://dx.doi.org/10.1186/cc10330 |
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