The clinical and functional relevance of microparticles induced by activated protein C treatment in sepsis

INTRODUCTION: Activated protein C (APC) induces release of microparticles (MP) from primary physiological cells, which are found in patients undergoing treatment with recombinant human APC (rhAPC) for severe sepsis. We hypothesised that APC on these circulating MPs activate endothelial protease-acti...

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Detalles Bibliográficos
Autores principales: Pérez-Casal, Margarita, Thompson, Victoria, Downey, Colin, Welters, Ingeborg, Wyncoll, Duncan, Thachil, Jecko, Toh, Cheng Hock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387637/
https://www.ncbi.nlm.nih.gov/pubmed/21834973
http://dx.doi.org/10.1186/cc10356

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