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Long-term treatment of osteoporosis: safety and efficacy appraisal of denosumab
Denosumab is a fully human monoclonal antibody to the receptor activator of nuclear factor-κB ligand (RANKL), a member of the tumor necrosis factor receptor superfamily essential for osteoclastogenesis. Denosumab treatment is associated with a rapid, sustained, and reversible reduction in bone turno...
Autores principales: | Anastasilakis, Athanasios D, Toulis, Konstantinos A, Polyzos, Stergios A, Anastasilakis, Chrysostomos D, Makras, Polyzois |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387828/ https://www.ncbi.nlm.nih.gov/pubmed/22767993 http://dx.doi.org/10.2147/TCRM.S24239 |
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