Myeloperoxidase deficiency preserves vasomotor function in humans

AIMS: Observational studies have suggested a mechanistic link between the leucocyte-derived enzyme myeloperoxidase (MPO) and vasomotor function. Here, we tested whether MPO is systemically affecting vascular tone in humans. METHODS AND RESULTS: A total of 12 135 patients were screened for leucocyte...

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Detalles Bibliográficos
Autores principales: Rudolph, Tanja K., Wipper, Sabine, Reiter, Beate, Rudolph, Volker, Coym, Anja, Detter, Christian, Lau, Denise, Klinke, Anna, Friedrichs, Kai, Rau, Thomas, Pekarova, Michaela, Russ, Detlef, Knöll, Kay, Kolk, Mandy, Schroeder, Bernd, Wegscheider, Karl, Andresen, Hilke, Schwedhelm, Edzard, Boeger, Rainer, Ehmke, Heimo, Baldus, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388013/
https://www.ncbi.nlm.nih.gov/pubmed/21724624
http://dx.doi.org/10.1093/eurheartj/ehr193

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