Fidaxomicin Is an Inhibitor of the Initiation of Bacterial RNA Synthesis

Fidaxomicin was recently approved for the treatment of Clostridium difficile infection. It inhibits transcription by bacterial RNA polymerase. Because transcription is a multistep process, experiments were conducted in which fidaxomicin was added at different stages of transcriptional initiation to...

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Detalles Bibliográficos
Autores principales: Artsimovitch, Irina, Seddon, Jaime, Sears, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Supplement Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388026/
https://www.ncbi.nlm.nih.gov/pubmed/22752861
http://dx.doi.org/10.1093/cid/cis358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388026/
https://www.ncbi.nlm.nih.gov/pubmed/22752861
http://dx.doi.org/10.1093/cid/cis358

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