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Multiple Novel Nesprin-1 and Nesprin-2 Variants Act as Versatile Tissue-Specific Intracellular Scaffolds

BACKGROUND: Nesprins (Nuclear envelope spectrin-repeat proteins) are a novel family of giant spectrin-repeat containing proteins. The nesprin-1 and nesprin-2 genes consist of 146 and 116 exons which encode proteins of ∼1mDa and ∼800 kDa is size respectively when all the exons are utilised in transla...

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Detalles Bibliográficos
Autores principales: Rajgor, Dipen, Mellad, Jason A., Autore, Flavia, Zhang, Qiuping, Shanahan, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388047/
https://www.ncbi.nlm.nih.gov/pubmed/22768332
http://dx.doi.org/10.1371/journal.pone.0040098

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