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BVT.2733, a Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Attenuates Obesity and Inflammation in Diet-Induced Obese Mice
BACKGROUND: Inhibition of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is being pursued as a new therapeutic approach for the treatment of obesity and metabolic syndrome. Therefore, there is an urgent need to determine the effect of 11β-HSD1 inhibitor, which suppresses glucocorticoid action, o...
Autores principales: | Wang, Long, Liu, Juan, Zhang, Aisen, Cheng, Peng, Zhang, Xiao, Lv, Shan, Wu, Lin, Yu, Jing, Di, Wenjuan, Zha, Juanmin, Kong, Xiaocen, Qi, Hanmei, Zhong, Yi, Ding, Guoxian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388048/ https://www.ncbi.nlm.nih.gov/pubmed/22768329 http://dx.doi.org/10.1371/journal.pone.0040056 |
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