Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase

Non-reproducible sequence artefacts are frequently detected in DNA from formalin-fixed and paraffin-embedded (FFPE) tissues. However, no rational strategy has been developed for reduction of sequence artefacts from FFPE DNA as the underlying causes of the artefacts are poorly understood. As cytosine...

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Detalles Bibliográficos
Autores principales: Do, Hongdo, Dobrovic, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388184/
https://www.ncbi.nlm.nih.gov/pubmed/22643842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388184/
https://www.ncbi.nlm.nih.gov/pubmed/22643842

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