NOXA as critical mediator for drug combinations in polychemotherapy

During polychemotherapy, cytotoxic drugs are given in combinations to enhance their anti-tumor effectiveness. For most drug combinations, underlying signaling mechanisms responsible for positive drug–drug interactions remain elusive. Here, we prove a decisive role for the Bcl-2 family member NOXA to...

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Detalles Bibliográficos
Autores principales: Ehrhardt, H, Höfig, I, Wachter, F, Obexer, P, Fulda, S, Terziyska, N, Jeremias, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388227/
https://www.ncbi.nlm.nih.gov/pubmed/22717582
http://dx.doi.org/10.1038/cddis.2012.53

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