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A novel role for RIP1 kinase in mediating TNFα production

Receptor-interacting protein 1 (RIP1) is a Ser/Thr kinase with both kinase-dependent and kinase-independent roles in death receptor signaling. The kinase activity of RIP1 is required for necroptosis, a caspase-independent pathway of programmed cell death. In some cell types, the inhibition of caspas...

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Detalles Bibliográficos
Autores principales:	Christofferson, D E, Li, Y, Hitomi, J, Zhou, W, Upperman, C, Zhu, H, Gerber, S A, Gygi, S, Yuan, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388236/ https://www.ncbi.nlm.nih.gov/pubmed/22695613 http://dx.doi.org/10.1038/cddis.2012.64

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