Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung

We present two cases of relapsed adenocarcinoma of the lung: a 50-year-old male and a 67-year-old male. Both patients had previously been treated with platinum-containing systemic chemotherapy. In both cases, significant clinical efficacy was demonstrated with combination chemotherapy consisting of...

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Autores principales: Wada, Sae, Fujimoto, Nobukazu, Gemba, Kenichi, Asano, Michiko, Fuchimoto, Yasuko, Ono, Katsuichiro, Ozaki, Shinji, Kishimoto, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388291/
https://www.ncbi.nlm.nih.gov/pubmed/22779020
http://dx.doi.org/10.1155/2012/821280
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author Wada, Sae
Fujimoto, Nobukazu
Gemba, Kenichi
Asano, Michiko
Fuchimoto, Yasuko
Ono, Katsuichiro
Ozaki, Shinji
Kishimoto, Takumi
author_facet Wada, Sae
Fujimoto, Nobukazu
Gemba, Kenichi
Asano, Michiko
Fuchimoto, Yasuko
Ono, Katsuichiro
Ozaki, Shinji
Kishimoto, Takumi
author_sort Wada, Sae
collection PubMed
description We present two cases of relapsed adenocarcinoma of the lung: a 50-year-old male and a 67-year-old male. Both patients had previously been treated with platinum-containing systemic chemotherapy. In both cases, significant clinical efficacy was demonstrated with combination chemotherapy consisting of pemetrexed, carboplatin, and bevacizumab as salvage treatment. Adverse events were mild. This regimen might be a viable therapeutic option even after heavy treatment such as platinum-containing chemotherapy, especially for patients with preserved organ function and good performance status.
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spelling pubmed-33882912012-07-09 Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung Wada, Sae Fujimoto, Nobukazu Gemba, Kenichi Asano, Michiko Fuchimoto, Yasuko Ono, Katsuichiro Ozaki, Shinji Kishimoto, Takumi Case Rep Oncol Med Case Report We present two cases of relapsed adenocarcinoma of the lung: a 50-year-old male and a 67-year-old male. Both patients had previously been treated with platinum-containing systemic chemotherapy. In both cases, significant clinical efficacy was demonstrated with combination chemotherapy consisting of pemetrexed, carboplatin, and bevacizumab as salvage treatment. Adverse events were mild. This regimen might be a viable therapeutic option even after heavy treatment such as platinum-containing chemotherapy, especially for patients with preserved organ function and good performance status. Hindawi Publishing Corporation 2012 2012-06-20 /pmc/articles/PMC3388291/ /pubmed/22779020 http://dx.doi.org/10.1155/2012/821280 Text en Copyright © 2012 Sae Wada et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wada, Sae
Fujimoto, Nobukazu
Gemba, Kenichi
Asano, Michiko
Fuchimoto, Yasuko
Ono, Katsuichiro
Ozaki, Shinji
Kishimoto, Takumi
Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung
title Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung
title_full Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung
title_fullStr Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung
title_full_unstemmed Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung
title_short Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung
title_sort successful treatment with pemetrexed, carboplatin, and bevacizumab for platinum-resistant adenocarcinoma of the lung
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388291/
https://www.ncbi.nlm.nih.gov/pubmed/22779020
http://dx.doi.org/10.1155/2012/821280
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