Reduction of voltage gated sodium channel protein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic neuropathy

BACKGROUND: Painful neuropathy is a common complication of diabetes. Previous studies have identified significant increases in the amount of voltage gated sodium channel isoforms Na(V)1.7 and Na(V)1.3 protein in the dorsal root ganglia (DRG) of rats with streptozotocin (STZ)-induced diabetes. We fou...

Descripción completa

Detalles Bibliográficos
Autores principales: Chattopadhyay, Munmun, Zhou, Zhigang, Hao, Shuanglin, Mata, Marina, Fink, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388457/
https://www.ncbi.nlm.nih.gov/pubmed/22439790
http://dx.doi.org/10.1186/1744-8069-8-17

Ejemplares similares

Ejemplares similares