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The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration

Cells often migrate in vivo in an extracellular matrix that is intrinsically three-dimensional (3D) and the role of actin filament architecture in 3D cell migration is less well understood. Here we show that, while recently identified linkers of nucleoskeleton to cytoskeleton (LINC) complexes play a...

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Detalles Bibliográficos
Autores principales: Khatau, Shyam B., Bloom, Ryan J., Bajpai, Saumendra, Razafsky, David, Zang, Shu, Giri, Anjil, Wu, Pei-Hsun, Marchand, Jorge, Celedon, Alfredo, Hale, Christopher M., Sun, Sean X., Hodzic, Didier, Wirtz, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388469/
https://www.ncbi.nlm.nih.gov/pubmed/22761994
http://dx.doi.org/10.1038/srep00488

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