Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies

Antibodies specific for histone post-translational modifications (PTMs) have been central to our understanding of chromatin biology. Here, we describe an unexpected and novel property of histone H4 site-specific acetyl antibodies in that they prefer poly-acetylated histone substrates. By all current...

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Detalles Bibliográficos
Autores principales: Rothbart, Scott B., Lin, Shu, Britton, Laura-Mae, Krajewski, Krzysztof, Keogh, Michael-C, Garcia, Benjamin A., Strahl, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388470/
https://www.ncbi.nlm.nih.gov/pubmed/22761995
http://dx.doi.org/10.1038/srep00489

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