c-Myc and EBV–LMP1: two opposing regulators of the HLA class I antigen presentation machinery in epithelial cells

BACKGROUND: Epstein–Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) up-regulates the human leukocyte antigen (HLA) class I antigen presentation machinery (APM). This appears counterintuitive with immune evasion in EBV-associated tumours like nasopharyngeal carcinoma (NPC). METHODS: Latent...

Descripción completa

Detalles Bibliográficos
Autores principales: Tudor, C S, Dawson, C W, Eckhardt, J, Niedobitek, G, Büttner, A C, Seliger, B, Hartmann, A, Buettner, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388564/
https://www.ncbi.nlm.nih.gov/pubmed/22588558
http://dx.doi.org/10.1038/bjc.2012.197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388564/
https://www.ncbi.nlm.nih.gov/pubmed/22588558
http://dx.doi.org/10.1038/bjc.2012.197

Ejemplares similares