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c-Myc and EBV–LMP1: two opposing regulators of the HLA class I antigen presentation machinery in epithelial cells

BACKGROUND: Epstein–Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) up-regulates the human leukocyte antigen (HLA) class I antigen presentation machinery (APM). This appears counterintuitive with immune evasion in EBV-associated tumours like nasopharyngeal carcinoma (NPC). METHODS: Latent...

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Detalles Bibliográficos
Autores principales:	Tudor, C S, Dawson, C W, Eckhardt, J, Niedobitek, G, Büttner, A C, Seliger, B, Hartmann, A, Buettner, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388564/ https://www.ncbi.nlm.nih.gov/pubmed/22588558 http://dx.doi.org/10.1038/bjc.2012.197

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