Regioselective chlorination and bromination of unprotected anilines under mild conditions using copper halides in ionic liquids

By using ionic liquids as solvents, the chlorination or bromination of unprotected anilines at the para-position can be achieved in high yields with copper halides under mild conditions, without the need for potentially hazardous operations such as supplementing oxygen or gaseous HCl.

Detalles Bibliográficos
Autores principales: Wang, Han, Wen, Kun, Nurahmat, Nurbiya, Shao, Yan, Zhang, He, Wei, Chao, Li, Ya, Shen, Yongjia, Sun, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388862/
https://www.ncbi.nlm.nih.gov/pubmed/23015822
http://dx.doi.org/10.3762/bjoc.8.84
Descripción
Sumario:By using ionic liquids as solvents, the chlorination or bromination of unprotected anilines at the para-position can be achieved in high yields with copper halides under mild conditions, without the need for potentially hazardous operations such as supplementing oxygen or gaseous HCl.

Ejemplares similares