Cargando…
Parallel and four-step synthesis of natural-product-inspired scaffolds through modular assembly and divergent cyclization
By emulating the universal biosynthetic strategy, which employs modular assembly and divergent cyclizations, we have developed a four-step synthetic process to yield a collection of natural-product-inspired scaffolds. Modular assembly of building blocks onto a piperidine-based manifold 6, having a c...
Autores principales: | Oguri, Hiroki, Mizoguchi, Haruki, Oikawa, Hideaki, Ishiyama, Aki, Iwatsuki, Masato, Otoguro, Kazuhiko, Ōmura, Satoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388883/ https://www.ncbi.nlm.nih.gov/pubmed/23015843 http://dx.doi.org/10.3762/bjoc.8.105 |
Ejemplares similares
-
Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies
por: Sennari, Goh, et al.
Publicado: (2017) -
Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid
por: Noguchi, Yoshihiko, et al.
Publicado: (2016) -
Zn(OTf)(2)-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds
por: Yorimoto, Sadaiwa, et al.
Publicado: (2019) -
Diatretol, an α, α′-dioxo-diketopiperazine, is a potent in vitro and in vivo antimalarial
por: Ishiyama, Aki, et al.
Publicado: (2021) -
Structure-Activity Relationship between Thiol Group-Trapping Ability of Morphinan Compounds with a Michael Acceptor and Anti-Plasmodium falciparum Activities
por: Kutsumura, Noriki, et al.
Publicado: (2020)