Upregulation of heparanase in high-glucose-treated endothelial cells promotes endothelial cell migration and proliferation and correlates with Akt and extracellular-signal-regulated kinase phosphorylation

PURPOSE: The objectives of this study were to determine whether high-glucose-induced upregulation of heparanase (HPSE) expression and differential heparanase expression in human retinal vascular endothelial cells (HRECs) can alter HREC migration and proliferation. We also aimed to determine whether...

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Detalles Bibliográficos
Autores principales: Yuan, Ling, Hu, Jie, Luo, Yan, Liu, QingYun, Li, Tao, Parish, Christopher R., Freeman, Craig, Zhu, XiaoBo, Ma, Wei, Hu, XuTing, Yu, HongHua, Tang, ShiBo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388982/
https://www.ncbi.nlm.nih.gov/pubmed/22773906

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