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Gq/11-Mediated Signaling and Hypertrophy in Mice with Cardiac-Specific Transgenic Expression of Regulator of G-Protein Signaling 2

Cardiac hypertrophy is a well-established risk factor for cardiovascular morbidity and mortality. Activation of G(q/11)-mediated signaling is required for pressure overload-induced cardiomyocyte (CM) hypertrophy to develop. We previously showed that among Regulators of G protein Signaling, RGS2 sele...

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Detalles Bibliográficos
Autores principales: Park-Windhol, Cindy, Zhang, Peng, Zhu, Ming, Su, Jialin, Chaves, Leonard, Maldonado, Angel E., King, Michelle E., Rickey, Lisa, Cullen, Darragh, Mende, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388988/
https://www.ncbi.nlm.nih.gov/pubmed/22802950
http://dx.doi.org/10.1371/journal.pone.0040048