Cargando…

Identification of Factors Contributing to Variability in a Blood-Based Gene Expression Test

BACKGROUND: Corus CAD is a clinically validated test based on age, sex, and expression levels of 23 genes in whole blood that provides a score (1–40 points) proportional to the likelihood of obstructive coronary disease. Clinical laboratory process variability was examined using whole blood controls...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elashoff, Michael R., Nuttall, Rachel, Beineke, Philip, Doctolero, Michael H., Dickson, Mark, Johnson, Andrea M., Daniels, Susan E., Rosenberg, Steven, Wingrove, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388994/ https://www.ncbi.nlm.nih.gov/pubmed/22802952 http://dx.doi.org/10.1371/journal.pone.0040068

Ejemplares similares

A whole blood gene expression-based signature for smoking status
por: Beineke, Philip, et al.
Publicado: (2012)

Evaluation of a solid matrix for collection and ambient storage of RNA from whole blood
por: Tao, Heng, et al.
Publicado: (2014)

Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients
por: Elashoff, Michael R, et al.
Publicado: (2011)

Biological and Analytical Stability of a Peripheral Blood Gene Expression Score for Obstructive Coronary Artery Disease in the PREDICT and COMPASS Studies
por: Daniels, Susan E., et al.
Publicado: (2014)

Global analysis of X-chromosome dosage compensation
por: Gupta, Vaijayanti, et al.
Publicado: (2006)

Peripheral blood gene expression signatures which reflect smoking and aspirin exposure are associated with cardiovascular events
por: Wingrove, James A., et al.
Publicado: (2018)

A survey of ovary-, testis-, and soma-biased gene expression in Drosophila melanogaster adults
por: Parisi, Michael, et al.
Publicado: (2004)

Variable blood processing procedures contribute to plasma proteomic variability
por: Halvey, Patrick, et al.
Publicado: (2021)

Coronary Atherosclerotic Plaque Detected by Computed Tomographic Angiography in Subjects with Diabetes Compared to Those without Diabetes
por: Khazai, Bahram, et al.
Publicado: (2015)

FlyGEM, a full transcriptome array platform for the Drosophila community
por: Johnston, Rick, et al.
Publicado: (2004)

Whole Blood Gene Expression Testing for Coronary Artery Disease in Nondiabetic Patients: Major Adverse Cardiovascular Events and Interventions in the PREDICT Trial
por: Rosenberg, Steven, et al.
Publicado: (2012)

Clinical Implications of Referral Bias in the Diagnostic Performance of Exercise Testing for Coronary Artery Disease
por: Ladapo, Joseph A., et al.
Publicado: (2013)

Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection
por: Thänert, Robert, et al.
Publicado: (2017)

Flow Heterogeneity and Factors Contributing to the Variability in Retinal Capillary Blood Flow
por: Neriyanuri, Srividya, et al.
Publicado: (2023)

Can Ambulatory Blood Pressure Variability Contribute to Individual Cardiovascular Risk Stratification?
por: Magdás, Annamária, et al.
Publicado: (2016)

Unconventional Pathways of Secretion Contribute to Inflammation
por: Daniels, Michael J. D., et al.
Publicado: (2017)

Edward Jenner
por: Wingrove, Hy.
Publicado: (1922)

Whole blood RNA extraction efficiency contributes to variability in RNA sequencing data sets
por: Wilfinger, William W., et al.
Publicado: (2023)

Identification of variables contributing to superovulation efficiency for production of transgenic prairie voles (Microtus ochrogaster)
por: Keebaugh, Alaine C, et al.
Publicado: (2012)

Routine Laboratory Blood Tests May Diagnose Significant Fibrosis in Liver Transplant Recipients with Chronic Hepatitis C: A 10 Year Experience
por: Sheen, Victoria, et al.
Publicado: (2016)

Identification of lung cancer with high sensitivity and specificity by blood testing
por: Leidinger, Petra, et al.
Publicado: (2010)

Química orgánica
por: Wingrove, Alan S., 1939-
Publicado: (1984)

Organic chemistry
por: Wingrove, Alan S., 1939-
Publicado: (1981)

Arterial Blood Pressure Variability and Other Vascular Factors Contribution to the Cognitive Decline in Parkinson’s Disease
por: Pierzchlińska, Anna, et al.
Publicado: (2021)

Dietary Protein and the Blood Glucose Concentration
por: Nuttall, Frank Q., et al.
Publicado: (2013)

Metformin May Contribute to Inter-individual Variability for Glycemic Responses to Exercise
por: Malin, Steven K., et al.
Publicado: (2020)

Explainable Artificial Intelligence for COVID-19 Diagnosis Through Blood Test Variables
por: Thimoteo, Lucas M., et al.
Publicado: (2022)

The Contribution of Shape Features and Demographic Variables to Disembedding Abilities
por: Cappello, Elisa Morgana, et al.
Publicado: (2022)

A Critical Analysis of the Clinical Use of Incretin-Based Therapies : Are the GLP-1 therapies safe?
por: Butler, Peter C., et al.
Publicado: (2013)

Caloric Restriction and Its Effect on Blood Pressure, Heart Rate Variability and Arterial Stiffness and Dilatation: A Review of the Evidence
por: Nicoll, Rachel, et al.
Publicado: (2018)

Red Blood Cell Contribution to Hemostasis
por: Gillespie, Andrea H., et al.
Publicado: (2021)

Training Self-Administered Acupressure Exercise among Postmenopausal Women with Osteoarthritic Knee Pain: A Feasibility Study and Lessons Learned
por: Zhang, Yan, et al.
Publicado: (2012)

Differential Contributions of the Complement Anaphylotoxin Receptors C5aR1 and C5aR2 to the Early Innate Immune Response against Staphylococcus aureus Infection
por: Horst, Sarah A., et al.
Publicado: (2015)

Contribution of behavioural variability to representational drift
por: Sadeh, Sadra, et al.
Publicado: (2022)

Effect of Restricting Perimetry Testing Algorithms to Reliable Sensitivities on Test-Retest Variability
por: Gardiner, Stuart K., et al.
Publicado: (2016)

Fault Identification of Chemical Processes Based on k-NN Variable Contribution and CNN Data Reconstruction Methods
por: Wang, Guo-Zhu, et al.
Publicado: (2019)

Two Independent Contributions to Step Variability during Over-Ground Human Walking
por: Collins, Steven H., et al.
Publicado: (2013)

Association of heart rate variability, blood pressure variability, and baroreflex sensitivity with gastric motility at rest and during cold pressor test
por: Prakash, Kiran, et al.
Publicado: (2021)

Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses
por: Gunawardana, Hasitha, et al.
Publicado: (2021)

Prevalence and Variability in Medications Contributing to Polypharmacy in Long-Term Care Facilities
por: Jokanovic, Natali, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4k87jvfnco634vu60hdeg83ubd