Cargando…

Partial Regulatory T Cell Depletion Prior to Schistosomiasis Vaccination Does Not Enhance the Protection

CD4(+)CD25(+) regulatory T cells (Tregs) do not only influence self-antigen specific immune responses, but also dampen the protective effect induced by a number of vaccines. The impact of CD4(+)CD25(+) Tregs on vaccines against schistosomiasis, a neglected tropical disease that is a major public hea...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xuefeng, Liu, Fan, Zhou, Sha, Xu, Zhipeng, Hoellwarth, Jason, Chen, Xiaojun, He, Lei, Zhang, Rongbo, Liu, Feng, Wang, Jun, Su, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389001/
https://www.ncbi.nlm.nih.gov/pubmed/22802961
http://dx.doi.org/10.1371/journal.pone.0040359