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Safety and Immunogenicity of rSh28GST Antigen in Humans: Phase 1 Randomized Clinical Study of a Vaccine Candidate against Urinary Schistosomiasis

BACKGROUND: Treatment of urinary schistosomiasis by chemotherapy remains challenging due to rapid re-infection and possibly to limited susceptibility to praziquantel treatment. Therefore, therapeutic vaccines represent an attractive alternative control strategy. The objectives of this study were to...

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Detalles Bibliográficos
Autores principales: Riveau, Gilles, Deplanque, Dominique, Remoué, Franck, Schacht, Anne-Marie, Vodougnon, Hubert, Capron, Monique, Thiry, Michel, Martial, Joseph, Libersa, Christian, Capron, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389022/
https://www.ncbi.nlm.nih.gov/pubmed/22802974
http://dx.doi.org/10.1371/journal.pntd.0001704