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12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity
12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) is an enzymatic product of prostaglandin H(2) (PGH(2)) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. Despite the high level of 12-HHT present in tissues and bodily fluids, its precise function remains largely unknown....
Autores principales: | Lee, Jin-Wook, Ryu, Ho-Cheol, Ng, Yee Ching, Kim, Cheolmin, Wei, Jun-Dong, Sabaratnam, Vikineswary, Kim, Jae-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389076/ https://www.ncbi.nlm.nih.gov/pubmed/22391335 http://dx.doi.org/10.3858/emm.2012.44.6.043 |
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