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Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells

The proto-oncogenic protein c-Myb is an essential regulator of hematopoiesis and is frequently deregulated in hematological diseases such as lymphoma and leukemia. To gain insight into the mechanisms underlying the aberrant expression of c-Myb in myeloid leukemia, we analyzed and compared c-myb gene...

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Detalles Bibliográficos
Autores principales: Dassé, E, Volpe, G, Walton, D S, Wilson, N, Del Pozzo, W, O'Neill, L P, Slany, R K, Frampton, J, Dumon, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389162/
https://www.ncbi.nlm.nih.gov/pubmed/22829978
http://dx.doi.org/10.1038/bcj.2012.20

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