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High TOP2B/TOP2A expression ratio at diagnosis correlates with favourable outcome for standard chemotherapy in acute myeloid leukaemia

BACKGROUND: Cytosine arabinoside-based chemotherapy coupled with anthracycline is currently the first-line treatment for acute myeloid leukaemia (AML), but diverse responses to the regimen constitute obstacles to successful treatment. Therefore, outcome prediction to chemotherapy at diagnosis is bel...

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Detalles Bibliográficos
Autores principales:	Song, J H, Kweon, S H, Kim, H-J, Lee, T-H, Min, W-S, Kim, Y-K, Hwang, S Y, Kim, T S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389410/ https://www.ncbi.nlm.nih.gov/pubmed/22627319 http://dx.doi.org/10.1038/bjc.2012.206

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