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Even-skipped homeobox 1 is frequently hypermethylated in prostate cancer and predicts PSA recurrence

BACKGROUND: DNA methylation is an important epigenetic mechanism in prostate cancer (PCa) progression. Given the role of even-skipped homeobox 1 (EVX1) in the regulation of multiple genes during embryogenesis, we postulated that EVX1 methylation is altered in PCa progression. METHODS: Bisulphite seq...

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Detalles Bibliográficos
Autores principales:	Truong, M, Yang, B, Wagner, J, Kobayashi, Y, Rajamanickam, V, Brooks, J, Jarrard, D F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389415/ https://www.ncbi.nlm.nih.gov/pubmed/22596233 http://dx.doi.org/10.1038/bjc.2012.216

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