Leg length, sitting height and postmenopausal breast cancer risk

BACKGROUND: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. METHODS: From the prospective Danish cohort ‘Diet, Cancer and Health’, 23 864 postmenopausal women enrolled...

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Detalles Bibliográficos
Autores principales: Mellemkjær, L, Christensen, J, Frederiksen, K, Baker, J L, Olsen, A, Sørensen, T I A, Tjønneland, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389429/
https://www.ncbi.nlm.nih.gov/pubmed/22677900
http://dx.doi.org/10.1038/bjc.2012.244
Descripción
Sumario:BACKGROUND: Tallness has consistently been associated with an increased risk of breast cancer. We investigated the association further by decomposing height into leg length and sitting height. METHODS: From the prospective Danish cohort ‘Diet, Cancer and Health’, 23 864 postmenopausal women enrolled during 1993–1997 were followed for a diagnosis of breast cancer in the Danish Cancer Registry through 2009. RESULTS: The incidence rate ratios for breast cancer were 1.11 (95% CI=1.06–1.16) for each 5 cm increase in total height and 1.09 (95% CI=1.01–1.17) and 1.14 (95% CI=1.04–1.25) for each 5 cm increase in leg length and sitting height, respectively. There was no statistical significant difference between the associations for leg length and sitting height (P=0.47). CONCLUSION: Leg length does not seem to be more strongly associated with breast cancer among postmenopausal women than sitting height.

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